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Because of the increased use of atriums focusing on their
2018-10-22
Because of the increased use of atriums, focusing on their design aspects has become important. Atriums have certain characteristics that differentiate them from other atriums. Although globalization has resulted in many similarities in the configurations of shopping centers and atriums around the w
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br Conclusion br Introduction br Case report A year old
2018-10-22
Conclusion Introduction Case report A 38-year-old woman was injured in a domestic dispute with her ex-husband. She was stabbed in her belly and splashed with sulfuric acid. Upon presentation to our emergency department, a physical examination showed one 5-cm-long, longitudinal, penetrating
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br Introduction Carcinoma cuniculatum was first
2018-10-22
Introduction Carcinoma cuniculatum was first described by Aird et al in 1954 as epithelioma cuniculatum. The name is derived from the Latin word cuniculus, meaning “rabbit,” because of its rabbit-burrow-like architecture (appearance of the complex branching of keratin-filled crypts). It is regard
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buy SB202190 Introduction br Sensing and quantification of
2018-10-22
Introduction Sensing and quantification of energy substances In 2012, the Nobel Prize in Chemistry was awarded to two American scientists Robert J. Lefkowitz and Brian K. Kobilka for their outstanding contribution to our understanding of G protein-coupled receptors (GPCRs). Absorption and quanti
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Seaweeds contain a variety of potentially bioactive compound
2018-10-22
Seaweeds contain a variety of potentially bioactive compounds some of which are not present in terrestrial plants. These compounds include, for example, proteins such as lectins or phycobiliproteins, carotenoids, pigments, polyphenols, phlorotannins and certain polysaccharides. They may have health-
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Both CAR and DAF have been
2018-10-22
Both CAR and DAF have been implicated in CVB infection. Molecular events underlying CVB entry have been described for polarized (Coyne and Bergelson, 2006) and nonpolarized tsa hdac (Patel et al., 2009). However, the exact mechanism involved in CVB infection of cardiomyocytes is unknown. Moreover, s
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br Results br Discussion As the first step of our
2018-10-22
Results Discussion As the first step of our method, hiPS cells underwent differentiation into definitive endoderm by treatment with activin A and the GSK3β inhibitor CHIR99021. In other methods, activin A and Wnt 3a have mainly been used to induce definitive endoderm (D\'Amour et al., 2006; K
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Our tissue localization studies Figs and confirmed the
2018-10-22
Our tissue localization studies (Figs. 1, 2 and 7) confirmed the restricted expression of αvβ5 within the limbus, and the fact that αvβ5-enriched LKB1 support higher CFE (Fig. 6) suggests that this integrin could be useful and an alternative LESC marker. We cannot accurately comment on whether αvβ5
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br Materials and methods br Results br Discussion Microglia
2018-10-20
Materials and methods Results Discussion Microglia are resident immune GSK2126458 in the CNS that regulate innate immunity and participate in adaptive immune response (Hanisch and Kettenmann, 2007). However, the roles of microglia in AD pathology are still under debate. While there is sign
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br Materials and methods br Acknowledgements We
2018-10-20
Materials and methods Acknowledgements We would like to thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the plasmids. Furthermore, we would like to thank Prof. Duncan R. Smith for proof reading the article. This work was supported by the Thailand Research Fund (MRG5980187), Nat
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In the current study we tested whether
2018-10-20
In the current study, we tested whether the potent Sirt1 activator SRT3025 (Miranda et al., 2015), a molecule that is structurally unrelated to resveratrol, could enhance hematopoiesis in Fancd2−/− mice. Materials and methods Results Discussion FA patients have fewer HSPCs and suffer from
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Introduction Osteoprogenitor cells are ubiquitous multipoten
2018-10-20
Introduction Osteoprogenitor cells are ubiquitous, multipotent stromal cells capable of differentiating into multiple cellular lineages [e.g. osteoblasts (responsible for secretion of the extracellular bone matrix) and osteocytes (mature bone cells)], and replenish existing local cell populations (
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The expression of T BRY
2018-10-20
The expression of T (BRY), taken as a marker of precursors of all mesodermal tissues, was here induced through the activation of the canonical Wnt signalling which has been identified as an inducer for the primitive streak. A novel GSK3β inhibitor compound, active at a lower concentration than that
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The induced expression of hADC was confirmed
2018-10-20
The induced expression of hADC was confirmed by immunostaining and western blotting (Fig. 1A&B). The over-expression of hADC genes significantly increased endogenous agmatine (Fig. 1C). Adherence of BTL-105 is important for differentiation as well as for proliferation, migration, neurite outgrowth,
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miR a has been extensively studied
2018-10-20
miR-29a has been extensively studied in different fields. miR-29a has been reported to be associated with cardiac hypertrophy and fibrosis (Roncarati et al., 2014), and functions as a negative regulator of extracellular matrix remodeling (van Rooij et al., 2008). We have previously reported that miR
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