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olda Supplier A variety of suitable murine xenograft
2018-10-24
A variety of suitable murine xenograft models are currently used in hematopoietic research, yet these animals require conditioning prior to experimentation. Given the increasingly restricted access to radiation sources, NBSGW mice are broadly enabling, allowing laboratories without access to radiati
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Based on these principles we speculated
2018-10-24
Based on these principles, we speculated that the use of rBC2LCN as a cargo of cytotoxic agent would provide an efficient strategy to eliminate hPSCs. Here we generated a recombinant lectin-toxin fusion protein by fusing rBC2LCN with 23 kDa of a catalytic domain of Pseudomonas aeruginosa exotoxin A
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br Experimental Procedures br Author Contributions
2018-10-24
Experimental Procedures Author Contributions Acknowledgments Introduction Induced pluripotent stem bch (iPSCs) have similar properties as embryonic stem cells (ESCs), such as self-renewal and differentiation capacity (Park et al., 2008c; Takahashi and Yamanaka, 2006). Reprogramming tech
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Using previously published expression data sets
2018-10-24
Using previously published expression data sets of 26 different tissues and cell types (Table S2), we generated a list of 100 genes reflecting tissues from all three germ layers as well as placental genes, reflecting an extraembryonic tissue (Table S3). Genes were chosen according to tissue specific
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br Results br Discussion As stem cells of
2018-10-24
Results Discussion As stem BTL105 of the skeleton, BM-MSC\'s lineage commitment, a crucial step thought to determine the yield of functional osteoblasts, needs to be tightly regulated. Yet how BM-MSC lineage commitment is regulated remains poorly understood. This study revealed that p38α MAPK
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br Introduction Hearing loss is the most common congenital s
2018-10-24
Introduction Hearing loss is the most common congenital sensory deficit (Chan et al., 2010). Approximately 1 child in 1,000 is affected with severe hearing loss at birth or during early childhood, and this is defined as prelingual deafness (Morton, 1991; Petersen and Willems, 2006), with about ha
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When we compared the in
2018-10-24
When we compared the in vivo MaSC activity using the gold standard mammary fat pad transplant assay, we found the CD24+ CD49fhi SCA-1neg cells had higher stem cell activity than the CD24+ CD49fhi SCA-1+ subset. Although the stem cell activity of the CD24+ CD49fhi SCA-1+ cells was limited (in vitro m
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In the current study we devised
2018-10-24
In the current study, we devised simple refinements to the conventional culture condition of Kubota et al. (2004b) that promotes utilization of glycolysis, which we have termed GO (glycolysis-optimized) conditions. To achieve this, we removed all supplementation of lipids and free fatty acids from t
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However to increase emission efficiency these hot electrons
2018-10-24
However, to increase emission efficiency, these hot electrons have to reach the outer emitter boundary and to remain in its vicinity for a relatively long time without relaxation. According to recent studies [65,66], such possibility appears if the considered medium is composed by nanoparticles with
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br When the hypothesis is true the distribution
2018-10-24
When the order NSC127716 Н∗ is true, the distribution of a quantity asymptotically approaches the χ-squared quantity with k degrees of freedom with an increase in sample size n, i.e. . Let us assume that the parameter vector is tested by the linear regression method: where Y is a column vector
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It is known that the displacements in the areas
2018-10-24
It is known that the displacements in the areas Ω1 and Ω2 in this case are harmonic functions: and the stresses in polar coordinates r and θ are determined by the formulae The stresses and the displacements on the line satisfy the conditions The solution for each problem can be found in the
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Since the function entering in integral takes the form
2018-10-24
Since the function entering in integral (27) takes the form in a symmetric problem (when ), the stress singularity with r → 0 occurs when the angle governing the region with the harder material exceeds 180°. Conclusion Introduction The lipoxygenase of plastic flow, which has currently gaine
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br Results Table shows the characteristics
2018-10-24
Results Table 1 shows the characteristics of the study participants by gender. Occupational position differed significantly by gender. Compared to women, men were more likely to be manual/service workers and professionals/managers, and were less likely to be clerks and associate-professionals. Me
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A second and perhaps more philosophical implication
2018-10-24
A second and perhaps more philosophical implication of our findings relates to the vital importance of social connections, trust and tolerance in our communities. These are hallmarks of social capital, and yet social, political and media commentary often laments their erosion in this modern era of s
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While our findings contribute to this relatively recent body
2018-10-24
While our findings contribute to this relatively recent body of work around multimorbidity across the life course, they should be interpreted in context. The NHIS is a nationally representative sample that allows a population-level examination of correlates of multimorbidity. The cross-sectional nat
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