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The main idea behind space
2018-10-29
The main idea behind space syntax spatial elements is “that people experience their environment in certain geometries: they pkm2 move in lines [axial lines], interact in convex spaces [convex spaces], and sees changeable panoptical views when moving around [isovists]” (Akkelies, 2011). By investiga
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br Conclusion br Utzon s Chinese architecture Utzon
2018-10-29
Conclusion Utzon׳s Chinese architecture Utzon׳s interest in China and his pursuit for modernity foreshadowed a deeply rooted inner conflict, which is manifested in the chronology of his life and the three houses that he designed and built for his family. Throughout his lifetime, Utzon was much
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The organizing principles of space signify interpersonal
2018-10-29
The organizing principles of space signify interpersonal relationships as much as they indicate the general state of mankind (Tuan, 1977). Therefore, lifestyle highly depends on one׳s ownership of a private space (Rossler et al., 2005; Hanson, 2008). In addition, the needs and abilities of residents
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Introduction For decades local cities in Japan have experien
2018-10-29
Introduction For decades, local cities in Japan have experienced a hollowing-out problem. Since the 2016 revision of the “three town development laws,” including the City Planning Act, the Act on the Measures by Large-Scale Retail Stores for the Preservation of the Living Environment, and the Law o
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The diagnosis of suspected appendicitis remains challenging
2018-10-29
The diagnosis of suspected appendicitis remains challenging to physicians or surgeons in the emergency service. The state-of-the art diagnosis of Ap involves the use of CT and ultrasonography. The accuracy of clinical diagnosis is approximately 80%, which corresponds to a negative appendectomy rate
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br Acknowledgments br Introduction Beh
2018-10-29
Acknowledgments Introduction Behçet\'s disease (BD) is an inflammatory disease characterized by recurrent oral aphthous ulcers and numerous potential systemic manifestations such as genital ulcers, enolase lesions, and ocular, neurologic, vascular, articular, and gastrointestinal diseases. Th
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Cryptosporidium s direct life cycle
2018-10-29
Cryptosporidium\'s direct life calcium calmodulin dependent protein kinase is enhanced by the existence of resistant oocysts that are capable of extended periods of survival in the environment. Thus, apart from person to person transmission by the faecal-oral route, oocysts can be transmitted in wa
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br Materials and methods br Results and discussions br
2018-10-29
Materials and methods Results and discussions Conclusion The capability of the CTs extracts to scavenge free radicals in different systems, indicating that they may be useful therapeutic agents for treating various chronic diseases which are more related to oxidative stress associated disea
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An important feature of stem cells is
2018-10-29
An important feature of stem opioid receptor is their ability to grow indefinitely in culture; hence, to shed light on this issue, cell doublings were monitored over time. The NPCs were capable of more than 60 population doublings without ceasing to proliferate, although an initially high prolifera
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Using our screening we were able to confirm the previously
2018-10-29
Using our screening, we were able to confirm the previously determined cytogenetic karyotypes of 34 mESC lines and to further validate our method using 19 additional mESC lines with unknown cytogenetic karyotypes. Our study includes the screening of five mESC lines that produced germline transmissio
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Although the CAG expansion in ATXN
2018-10-26
Although the CAG-expansion in ATXN3 is known to cause SCA3, the underlying cellular mechanisms leading to neurodegeneration are not fully elucidated. It has been proposed that the polyQ expansion alters normal ataxin-3 functions in for example endoplasmic reticulum associated degradation (ERAD) and
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In recent promising studies various stem cell types have
2018-10-26
In recent promising studies, various stem cell types have been used as an alternative source for BBB remodeling. Stem cells are self-renewable, can be subsequently differentiated into mature somatic cell types, and serve as a virtually unlimited independent cell source. In particular, hematopoietic
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In summary we report the robust differentiation
2018-10-26
In summary, we report the robust differentiation and subsequent transplantation of mESC-derived cone precursors (summarized in Figure S7). Cones differentiated in vitro following a specification sequence resembling that observed in vivo, indicating that mESC-derived retinal organoids represent a dev
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metabotropic glutamate receptor br Methods A scoping review
2018-10-26
Methods A scoping review determines the extent, range and nature of any research activity, making it a more suitable approach than a systematic review for this research question (Arksey & O’Malley, 2005; Levac, Colquhoun, & O’Brien, 2010). Given the complexity of the review design, a detailed pro
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In this paper we show that
2018-10-26
In this paper, we show that prisoners report worse health than their noninstitutionalized counterparts. Incarceration is associated with a higher prevalence of hypertension, diabetes, heart problems, asthma, kidney problems, stroke, arthritis, and STI, with differences larger for whites than blacks,
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