• In conclusion we demonstrated that cells with the standard

  2019-06-06

  

  In conclusion, we demonstrated that propyl with the standard Ph had no detectable BCR–ABL1 KD mutations and that they were responsive to imatinib therapy, while cells with the variant translocation harbored two KD mutations, a previously described one and a never previously reported one [5]. These c

• br Introduction Human endogenous retroviruses HERVs are gene

  2019-06-06

  

  Introduction Human endogenous retroviruses (HERVs) are genetic remnants of ancient retroviral infections of the germ line produced during primate evolution which are now transmitted vertically. To date, approximately 8% of the human genome is composed of such retroviral sequences [1]. Most HERVs

• In response to the lack of epidemiological

  2019-06-06

  

  In response to the lack of epidemiological information on typhoid in Africa, the Typhoid Fever Surveillance in Africa Programme (TSAP), funded by the Bill & Melinda Gates Foundation and covering ten countries and 13 sites across Africa, was established between 2010 and 2014. In this THZ1 issue of ,

• Regarding the pathophysiology of HF with preserved LVEF AF

  2019-06-06

  

  Regarding the pathophysiology of HF with preserved LVEF, AF is one of the most important precipitating factors related to diastolic dysfunction [22,23]. AF might have important roles in the pathogenesis of HF with preserved EF in association with diastolic HF. Compared with JCARE-CARD, which include

• br Discussion Variant angina was described by

  2019-06-06

  

  Discussion Variant XL184 was described by Prinzmetal et al. in 1959 [1]. It can involve serious arrhythmias such as ventricular tachycardia, ventricular fibrillation, and atrioventricular block, and patients are particularly susceptible to sudden cardiac death in such cases [2,3]. Coronary spast

• As Table shows all guidelines recommend OACs for

  2019-06-06

  

  As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec

• Surgery especially modified radical mastectomy is the gold s

  2019-06-06

  

  Surgery, especially modified radical mastectomy, is the “gold standard” for the treatment of male breast cancer. Postoperative adjuvant radiotherapy is recommended for male patients with large breast cancer and axillary lymph node and chest muscle involvement; it can reduce the risk of local cancer

• An ERP in the ECG has

  2019-06-06

  

  An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A

• To better understand how the

  2019-06-06

  

  To better understand how the unpaid status of internships at WHO headquarters might affect their international accessibility, together with past and present intern colleagues, we did an online survey during two summer intern cohorts (2011 and 2013). The survey, which was distributed via email to all

• br Approval statement br Role of the funding

  2019-06-05

  

  Approval statement Role of the funding source Conflict of interest Acknowledgments Introduction Osteosarcoma (OS) is the most common malignancy of bone, mainly affecting children, adolescents and young adults. According to the American Cancer Society, 750–900 new cases of OS are diagn

• Introduction Osteosarcoma OS is the most common

  2019-06-05

  

  Introduction Osteosarcoma (OS) is the most common primary malignant tumor of the bone. This neoplasm is defined histologically by osteoid deposition by the malignant mesenchymal sphingosine [1]. In OS, current evidence supports an osteoblastic population as the cell of origin [2], although the dist

• Introduction Dabigatran Boehringer Ingelheim Ingelheim

  2019-06-05

  

  Introduction Dabigatran (Boehringer Ingelheim, Ingelheim, Germany) is a direct thrombin inhibitor, which can be orally administered, and is used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). In early phase studies of dabigatran in healthy men, atp

• In September countries agreed to the ambitious Sustainable

  2019-06-05

  

  In September, 2015, 193 countries agreed to the ambitious Sustainable Development Goals (SDGs). SDG 3, for “healthy lives and wellbeing”, includes targets for universal health coverage (UHC). Some international commentators have raised questions about whether many of the SDGs are feasible and afford

• Intravenous injection of B F

  2019-06-05

  

  Intravenous injection of B16F10 melanoma cells in Nf-E2-/-mice produces markedly less lung metastatic lesions compared to that in wildtype mice [5]. This provides one of the strongest confirmations for the role of platelets in hematological dissemination of tumor cells although bone tissues were not

• Esta idea se reforz con uno de los

  2019-06-01

  

  Esta idea se reforzó con uno de los elementos identitarios oficiales de la organización, su propio escudo. La comil tomó cuatro de las características reconocibles del pgt histórico; es decir, las siglas, la estrella, la hoz y el martillo, y el círculo que enmarcó todos estos símbolos, mismos que de

14987 records 951/1000 page Previous Next First page 上5页 951952953954955 下5页 Last page