FUS also known as Translocated in Liposarcoma

2018-10-20

FUS, also known as Translocated in Liposarcoma (TLS), is a DNA/RNA-binding protein containing a glycine-rich region, an RNA recognition motif and a nuclear localization signal (Lattante et al., 2013; Yang et al., 2010). In FALS, more than 50 mutations in the FUS gene have been reported (Lattante et 

Interestingly this study of WASp deficient

2018-10-20

Interestingly, this study of WASp-deficient iPSCs, in comparison with their corrected cWAS-iPSC counterparts, revealed not only the expected functional defects in certain iPSC-derived hematopoietic progeny (e.g., NK cells), but also identified potential consequences for WASp deficiency in T and NK d

Our data suggest that the

2018-10-20

Our data suggest that the region where the duct transitions into an acinus harbors the meibomian gland progenitors, and localized hyperproliferation previously reported in this region (Parfitt et al., 2013) could constitute a transiently amplifying cell population. From this, we propose that LRCs ar

Previously it has been reported that iNPs

2018-10-20

Previously, it has been reported that iNPs can be directly converted from human or mouse FBs by TF combinations including all iPSC factor(s) (Lu et al., 2013), only certain factors (Wang et al., 2013; Yu et al., 2015), or single factors (Ring et al., 2012). Starting from a panel of 25 TFs, we identi

Hello world!

2018-07-29